SIGMA-ALDRICH CORPORATION Part No. C3630-100G
CAS Number: 6020-87-7 Empirical Formula (Hill Notation): C₄H₉N₃O₂ + H₂O Molecular Weight: 149.15 Beilstein Registry Number: 7942755 EC Number: 200-306-6 MDL Number: MFCD00071582 PubChem Substance ID: 24892629 Packaging 1 kg in poly bottle; 100 g in poly bottle Application Creatine (Cr) and phosphocreatine (PCr) are involved with rapid ATP production primarily in skeletal muscle tissue via the action of creatine kinase(s). Creatine may be used as a supplement to study its uptake mechanism and metabolism of action. Biochem/physiol Actions Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.